{"id":32205,"date":"2025-07-21T10:40:18","date_gmt":"2025-07-21T10:40:18","guid":{"rendered":"https:\/\/www.pulse-z.eu\/a-breakthrough-in-celiac-disease-a-new-global-standard-could-change-everything\/"},"modified":"2025-07-23T07:42:04","modified_gmt":"2025-07-23T07:42:04","slug":"prielom-v-liecbe-celiakie-novy-globalny-standard-by-mohol-zmenit-vsetko","status":"publish","type":"post","link":"https:\/\/www.pulse-z.eu\/sk\/prielom-v-liecbe-celiakie-novy-globalny-standard-by-mohol-zmenit-vsetko\/","title":{"rendered":"Prielom v lie\u010dbe celiakie: Nov\u00fd glob\u00e1lny \u0161tandard by mohol zmeni\u0165 v\u0161etko"},"content":{"rendered":"\n<p><span style=\"font-weight: 400;\">Celiac disease is more than just a gluten intolerance. It\u2019s a chronic, often invisible autoimmune condition that has long puzzled doctors and patients alike. But now, a scientific breakthrough might finally offer the clarity and precision needed to change the game \u2014 not only in diagnosis but also in daily management of the disease.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Thanks to a brand-new certified reference material developed by scientists at the EU\u2019s <\/span><a href=\"https:\/\/commission.europa.eu\/about\/departments-and-executive-agencies\/joint-research-centre_en\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Joint Research Centre<\/span><\/a><span style=\"font-weight: 400;\"> (JRC), we\u2019re one step closer to consistent, accurate testing for celiac disease worldwide.<\/span><\/p>\n<p> What Is Celiac Disease \u2014 And Why Is It So Hard to Diagnose? <\/p>\n<p><span style=\"font-weight: 400;\">Celiac disease affects genetically predisposed individuals whose immune systems react abnormally to gluten, a protein found in wheat, rye, and barley. When someone with celiac disease eats gluten, their immune system attacks the lining of the small intestine. Over time, this damages the tiny finger-like structures called villi, which help absorb nutrients.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The consequences? Nutrient deficiencies, anemia, skin and neurological issues, and in children, delayed growth.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s estimated that about 1% of the EU population \u2014 nearly 4.5 million people \u2014 live with celiac disease. But here\u2019s the catch: many don\u2019t even know it. Symptoms can vary widely or be misdiagnosed, and testing methods differ between countries and labs.<\/span><\/p>\n<p> Uncertainty in Testing: A Long-Standing Problem <\/p>\n<p><span style=\"font-weight: 400;\">Today\u2019s standard way of diagnosing celiac disease is through blood tests that measure specific antibodies \u2014 particularly anti-tTG antibodies. But here&#8217;s the issue: different labs use different tests, machines, and result interpretations. That means one person\u2019s test results might look completely different depending on where they\u2019re tested.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This lack of consistency often leads to delayed or incorrect diagnoses, making patients feel lost and frustrated.<\/span><\/p>\n<p> A World-First Standard That Could Change Everything <\/p>\n<p><span style=\"font-weight: 400;\">Enter the first-ever <\/span><a href=\"https:\/\/joint-research-centre.ec.europa.eu\/jrc-news-and-updates\/first-ever-certified-reference-material-improve-diagnosis-coeliac-disease-2025-05-19_en\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">certified reference material<\/span><\/a><span style=\"font-weight: 400;\"> for celiac diagnostics \u2014 developed by the Joint Research Centre (JRC) in collaboration with the UK\u2019s Medicines and Healthcare Products Regulatory Agency.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This new standard sets a global benchmark. It\u2019s already been recognized by the World Health Organization (WHO) as an international standard for anti-tTG antibodies. One batch will be used by WHO, and the other will be distributed by the JRC to laboratories around the world.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Why is this such a big deal? Because now, test results from Berlin to Bucharest to Barcelona can be measured against the same reliable reference point. Doctors get better tools. Labs get consistent readings. And patients get faster, more accurate diagnoses.<\/span><\/p>\n<p> Responding to a Global Clinical Need <\/p>\n<p><span style=\"font-weight: 400;\">The need for this kind of standard wasn\u2019t random. The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) identified celiac disease as a priority for diagnostic harmonization.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">And with its long track record of creating reference materials, the JRC took on the challenge \u2014 successfully.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The result? A tool that not only helps detect celiac disease more reliably but also helps monitor treatment effectiveness over time. Because while there\u2019s no cure, celiac disease can be managed \u2014 if it\u2019s properly diagnosed.<\/span><\/p>\n<h3><b>Food Safety: The Second Front in the Celiac Battle<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Diagnosis is one thing. But for people with celiac disease, safe food is just as crucial. The only effective treatment is strict avoidance of gluten. That\u2019s why the accurate labeling of gluten content in food is vital \u2014 and often just as complex.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">EU regulations allow food to be labeled \u201cgluten-free\u201d if it contains less than 20 mg of gluten per kilogram. But recent JRC research shows that it\u2019s not always easy to prove that \u2014 especially with products like beer.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In fact, the team at JRC found that current testing methods can miss degraded gluten proteins that still trigger immune reactions. And without a consistent reference standard for gluten content, it\u2019s hard to trust the numbers.<\/span><\/p>\n<h3><b>Looking Ahead: From Diagnostics to Safer Foods<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">The JRC scientists are now calling for more in vivo toxicological studies and the development of new reference materials for food testing \u2014 similar to the ones that just revolutionized diagnostics.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because whether it\u2019s about identifying disease or choosing a safe snack, it all comes down to one thing: reliable, science-based standards.<\/span><\/p>\n<h3><b>Why This Matters \u2014 Especially for Young People<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">You might not hear about celiac disease every day, but for millions of Europeans \u2014 including young people \u2014 it\u2019s a life-defining condition.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This new certified reference material is a major win for health equality and scientific precision. It means fewer misdiagnoses, faster treatment, and more confidence in what you eat.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In a world where evidence-based healthcare is more important than ever, this breakthrough is a reminder of what science \u2014 and European cooperation \u2014 can achieve.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Better tools. Better health. And a clearer path forward for those living with celiac disease.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Celiac disease is more than just a gluten intolerance. It\u2019s a chronic, often invisible autoimmune condition that has long puzzled doctors and patients alike. But now, a scientific breakthrough might finally offer the clarity and [&hellip;]<\/p>\n","protected":false},"author":158,"featured_media":28348,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[723],"tags":[4637,4638,4639,4640,1178,4641,4642,4643,4644,4645,4646,4647],"post_formats":[673],"coauthors":[3870],"class_list":["post-32205","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rozmanitost-a-inkluzia","tag-autoimmune-diseases-sk","tag-celiac-disease-sk","tag-diagnostics-sk","tag-eu-science-sk","tag-european-union-sk","tag-food-safety-sk","tag-gluten-intolerance-sk","tag-gluten-free-sk","tag-health-innovation-sk","tag-jrc-sk","tag-medical-research-sk","tag-youth-health-sk","post_formats-clanky"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/posts\/32205","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/users\/158"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/comments?post=32205"}],"version-history":[{"count":2,"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/posts\/32205\/revisions"}],"predecessor-version":[{"id":32207,"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/posts\/32205\/revisions\/32207"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/media\/28348"}],"wp:attachment":[{"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/media?parent=32205"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/categories?post=32205"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/tags?post=32205"},{"taxonomy":"post_formats","embeddable":true,"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/post_formats?post=32205"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.pulse-z.eu\/sk\/wp-json\/wp\/v2\/coauthors?post=32205"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}